A study carried out by Sarrià's Chemical Institute (IQS) has opened the door to being able to diagnose and treat cancer, with infrared light. The study, that has been published in the magazine cover of the magazine “Chemical Communications”, of the Royal Society of Chemistry of London, there has been realized by the teacher of Physical Chemistry of the IQS, Santi Nonell, the expert in organic synthesis, Thibault Gallavardin, and the investigative PhD student of the IQS, Oriol Planas.
A cell of cancer being divided
The study, developed by the Laboratory of Photochemical of IQS, has discovered a new chemical reaction, in which a fluorescent probe changes color when it joins an antibody and other biomolecules of medical interest, as well as to a wide range of nanoparticles.
As has reported the IQS, scientific university of the Jesuits, the marking antibody, biomolecules and nanoparticles, with fluorescent probes, it is a technique that is in use, in clinical tests and in diagnosis for image.
Recently also it is started using for guiding surgical interventions, in real time; but one of the principal problems of the probes, nowadays, available is that its emissionis, in the visible zone of the spectrum, and is overlapped by the typical autofluorescence of the biological fabrics.
However, the fluorogenic probes, developed in the IQS, solve this problem, due to the fact that the change of color allows to separate the probes, joined the antibody, those who could have been separated.
On the other hand, its emission takes place in the zone of the infrared nearby one, a fact that fills an emptiness, nowadays existing in this zone of the spectrum.
Besides its fluorescent properties, the probes, joined the antibody, can be activated by light, to generate some reactivate forms of oxygen and hostesses induce the death of the cells, with high selectivity and efficiency, it has been explained by the IQS.
"This double diagnostic and therapeutic slope they awards a high potential as agents teranóstics for fotoimmunotherapy", have indicated the researchers.
Well, I think it is very interesting for any therapy. I hope that you have liked this news.
Until my next post, kind regards,
Luis.
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