I have just found a very interesting news for all of us, because it is a step up.
Researchers, at the National Center for Cardiovascular Research (CNIC), have been discovered using the zebrafish, that telomerase is rapidly activated, after cardiac injury, which is key to the regeneration of the heart, according to the results, published in the journal Cell Reports.
A zebradish
After a heart attack, the body undergoes significant consequences as the part of the heart affected by myocardial heals and stops beating. However, there are other species, that a heart attack will not mean a big problem, as with zebrafish.
In these cases, the heart has the amazing ability to recover, after cardiac injury, as heart cells are divided, rapidly, after injury; then, the damaged muscle is replaced, in a short space of time.
In the current work, the researchers from the CNIC have found that the key is in the enzyme telomerase, which is responsible for maintaining the ends of chromosomes, called telomeres too.
Each time a cell is divided, the chromosomes become shorter. If these chromosomes become too short, it can lead to the cell, that has, to malfunction or even die. Telomerase counteract this shortening, helping re-establish the correct length of the chromosome.
This research shows how the telomerase of the zebrafish is fast "hyperactived" , in the heart cells, after an injury. This activation is essential, in the process of the cardiac regeneration of the fish. To demonstrate it, this enzyme has been inactivated and it has been found that the cells were no longer divided and DNA damage increased.
These results may indicate a new way to treat cardiac damage, as temporary and controlled activation of telomerase could be a strategy study, for the treatment of patients, who have suffered a heart attack.
Well, I have been surprised by this news and I hope that you have liked it, such as I did,
Until my next post, kind regards,
Luis.
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