I have just found a very interesting and encouraging news: "Broccoli has pharmaceutical properties to treat chronic lymphocytic Leukemia". And this has been discovered, in Spain.
Broccoli
A study, led by the Higher Council for Scientific Research (CSIC) and with the participation of the Gregorio Marañón hospital and the Princess hospital, both of Madrid, has discovered the pharmaceutical properties of indole-3-carbinol, for chronic lymphocytic Leukemia. It is a natural compound, which is present in plants of the genus brassicas, such as broccoli, cabbage, cauliflower and Brussels sprouts.
Although the body well tolerate this compound, it has a toxic effect on certain Leukemia cells. The results were published in the journal “Clinical Cancer Research”.
In the in vitro study, have been used cells of patients with chronic lymphatic Leukemia, with different phases and prognosis. The data show that, through the drugs, can be achieved concentrations of this compound, causing death of leukemic cells; but not of normal lymphocytes, "essential in the immune system". The study's authors also note that indole-3-carbinol "significantly improves" the effect of the fludarabine, one of the most use compounds, in the treatment of this type of Leukemia, even in patients with resistance to this drug.
"The results indicate that the indole-3-carbinol enhances the therapeutic activity of the fludarabine and other drugs. Therefore, these combinated therapies could be used to combat chronic lymphocytic Leukemia, even in patients who have developed recurrences and multidrug resistance to standard treatments", says Juan Manuel Zapata, researcher from the CSIC, at the Institute of Biomedical Research "Alberto Sols".
Last September 2014, Zapata and Gema Pérez --scientific from the same centre of research-- registered patent of the indole-3-carbinol, as a new drug, capable of acting against diseases, such as chronic lymphocytic Leukemia and the Burkitt lymphoma. This compound is a potent toxic, against some tumor cells.
One of the main features, offered by this compound, is its action against cancer cells, in patients with different stages of disease and in those with resistance to treatment. Its interaction, with the Fludarabine, reactivates and improves its effect on cells of patients, resistant to this drug.
Although, by the moment, this technology has not been visited, by a company, its possible oral administration and the existence of previous studies of toxicity, in humans, that demonstrate its high tolerance and low toxicity, could allow rapid clinical application.
Well, I hope that you think this news is such interesting as I do. Perhaps you do like eating Broccoli; if it is so, Congratulations!.
Until my next post, kind regards,
Luis.
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