The 90 per cent of Migraines can be treated and prevented with the administration of an enzyme called diAmine Oxidase (DAO), as demonstrated from a study by the Spanish Society of Deficit DAO and Capio General Hospital of Catalunya.
The study, which was brought under the “Infarma” Pharmaceutical Congress, held in Barcelona, is the first in the world to show that the administration of the DAO enzyme reduces migraines, as it was explained to EFE Agency by the lead researcher of this work, Joan Izquierdo Casas.
Migraine, which causes severe pain in one side of the head as well as visual and auditory discomfort, affecting 12 per cent of the population and 90 per cent of cases is that patients have a deficiency of the enzyme DAO.
By the way of visual discomfort, it is important to know that the "aura" occurs in one of every four patients with migraine; it lasts 20 to 60 minutes. When it disappears, there is a gap under an hour without symptoms and then begins the pain that corresponds to the next phase.
The most characteristic symptoms are the visuals, which can be very diverse, the most typical is to manifest as a scintillating scotoma consisting of a blind area of the visual field accompanied by a series of mobile light flashes.
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Scotoma in the middle of the visual field, trying to replicate the sensation experienced during the aura phase.
This enzyme (DAO) is responsible for degrading a molecule named “Histamine”, found in many foods, primarily those derived from milk and citrus fruits, and that is subsequently removed in the urine.
People with DAO deficit can not eliminate histamine, with which it passes to the blood and it is accumulated in the plasma, causing adverse effects such as gastrointestinal disorders and migraine.
Therefore, the treatment would ingest before meals a capsule DAO enzyme, "that creates no adverse effects or because addiction is a functional food, a drug not unlike analgesics", said Izquierdo.
The neurologist has insisted that patients with migraine and DAO deficit should also change their diet and avoid foods with more histamine. So, avoid processed foods, such as meats, dairy products, citrus fruits and alcoholic beverages as these, and contain much histamine, inhibit the enzyme DAO.
"I always sensed that there was a relationship among the consumption of certain foods and migraine," said Izquierdo; but so far had not been scientifically proven and the relationship is questioned by the Spanish Society of Neurology.
According Izquierdo, who belongs to this scientific society, the study presented today demonstrates scientifically that migraine patients improve if given the enzyme DAO.
The study looked for a year and a half a hundred cases of severe chronic migraine patients, who had between 9 and 14 episodes of pain per month, of which 81% were women and 19% of men in a proportion similar to that between the patients of this disease.
The average age of patients who participated in the research is 41 years old and have been chosen according to the diagnostic criteria of the International Headache Society.
The study was double-blind, that is, neither the patients nor the doctors knew which group was administered the enzyme and which group was given placebo.
Moreover, the neurologist Izquierdo stressed that migraine is not inherited, but what is transmitted genetically is the deficit DAO, is that in most cases just triggering a migraine, but not always.
Thus, migraine is related to 90 per cent of patients with this enzyme deficiency, while in other cases still unknown what causes it.
I hope that you think this new is interesting as I did.
Kind regards,
Luis.
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